| Pet Type | Weight | Recommended Daily Dose |
| Small Dog | Up to 30 lbs | 1 teaspoons (5 ml) |
| Medium Dog | 30-60 lbs | 1-1/2 teaspoons (8 ml) |
| Large Dog | 60-100 lbs | 2 teaspoons (10 ml) |
| Giant Dog | Over 100 lbs | 3 teaspoons (15 ml) |
| Cats | All Cat Sizes | 1/2 teaspoon (2 ml) |
All amounts may be doubled for hard-working dogs.
LubriSyn Dosage For Horses
Directions For Daily Oral Equine Use:
Complete results appear within 1-2 weeks of consistent use.
Maintenance: 1/2 ounce [15ml] per 1200 lbs once daily. Quantity can be doubled for initial 7 days or prior to competition.
Initial Load Period:
LubriSyn may be administered at double (30 ml) the daily maintenance level for an initial loading period of five days or more. Horses with joint health issues may benefit from an extended initial loading period of up to 14 days.
Pre-Performance Load:
LubriSyn may be administered at double (30 ml) the daily maintenance level for a pre-performance loading period of three days or more.
Contraindications:
There are no known contraindications for the use of LubriSyn oral gel in horses.
Toxicology: LubriSyn was administered at two, three and five times the recommended maintenance dosage of 75 mg daily for 90 days with no adverse effects upon hematology or clinical chemistry parameters observed.
Side Effects: There have been no local or systemic side effects observed in the field trials.
Directions For Daily Oral Equine Use:
Maintenance: 1/2 ounce (15 ml) per 1200 lbs once daily.
Quantity can be doubled for initial 7 days or prior to competition.
Chemistry:
Sodium hyaluronate, hyaluronic acid, hyaluronan and HA are terms for the same glycosaminoglycan that can exist in different forms depending on their chemical environment. This glycosaminoglycan is composed of repeating subunits of D-Glucuronic acid and N-Acetyl-D-Glucosamine connected with glycosidic bonds. Because LubriSyn (sodium hyaluronate) is extracted from a microbial source, it is free of dermatan, chondroitin sulfate and other glycosaminoglycan contamination.
Pharmacology:
HA is highly bio-compatible and bio-degradable. It regulates normal cellular constituents, decreasing the impact of exudation, enzyme release and subsequent degradation of joint integrity.
